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Single-molecule FRET TACKLE reveals highly dynamic mismatched DNA-MutS complexes
The first step in DNA mismatch repair (MMR) is the recognition of DNA mismatches or nucleotide insertions/deletions (IDLs) by MutS and MutS homologs. To investigate the conformational properties of MutS-mismatch complexes, we used single-molecule fluorescence resonance energy transfer (smFRET) to ex...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2857677/ https://ncbi.nlm.nih.gov/pubmed/20180598 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901871u |
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