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Covariate adjustment in randomized trials with binary outcomes: Targeted maximum likelihood estimation
Covariate adjustment using linear models for continuous outcomes in randomized trials has been shown to increase efficiency and power over the unadjusted method in estimating the marginal effect of treatment. However, for binary outcomes, investigators generally rely on the unadjusted estimate as th...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2857590/ https://ncbi.nlm.nih.gov/pubmed/18985634 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.3445 |
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