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Estimation and testing in targeted goup sequential covariate-adjusted randomized clinical trials

This article is devoted to the construction and asymptotic study of adaptive group sequential covariate-adjusted randomized clinical trials analyzed through the prism of the semipara-metric methodology of targeted maximum likelihood estimation (TMLE). We show how to build, as the data accrue group-s...

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Detalhes bibliográficos
Publicado no:Scand Stat Theory Appl
Main Authors: Chambaz, A., van der Laan, M. J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6084807/
https://ncbi.nlm.nih.gov/pubmed/30100663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/sjos.12013
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