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Retrovirally transduced murine T lymphocytes expressing FasL mediate effective killing of prostate cancer cells
Adoptively transferred T cells possess anticancer activities partially mediated by T-cell FasL engagement of Fas tumor targets. However, antigen-induced T-cell activation and clonal expansion, which stimulates FasL activity, is often inefficient in tumors. As a gene therapy approach to overcome this...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2857530/ https://ncbi.nlm.nih.gov/pubmed/19096446 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cgt.2008.96 |
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