Adenovirus-Mediated FasL Minigene Transfer Endows Transduced Cells with Killer Potential

Fas ligand (First apoptosis signal ligand, FasL, also known as CD95L) is the common executioner of apoptosis within the tumor necrosis factor (TNF) superfamily. We aimed to induce functional FasL expression in transduced cells using an adenovirus vector, which has the advantage of strong and transie...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Dumitrescu, Madalina, Trusca, Violeta Georgeta, Savu, Lorand, Stancu, Ioana Georgeta, Ratiu, Attila Cristian, Simionescu, Maya, Gafencu, Anca Violeta
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7504687/
https://ncbi.nlm.nih.gov/pubmed/32825521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21176011
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