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Retrovirally transduced murine T lymphocytes expressing FasL mediate effective killing of prostate cancer cells

Adoptively transferred T cells possess anticancer activities partially mediated by T-cell FasL engagement of Fas tumor targets. However, antigen-induced T-cell activation and clonal expansion, which stimulates FasL activity, is often inefficient in tumors. As a gene therapy approach to overcome this...

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Detalhes bibliográficos
Main Authors: Symes, JC, Siatskas, C, Fowler, DH, Medin, JA
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857530/
https://ncbi.nlm.nih.gov/pubmed/19096446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cgt.2008.96
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