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Gemcitabine sensitizes lung cancer cells to Fas/FasL system-mediated killing

Gemcitabine is a chemotherapy agent commonly used in the treatment of non-small cell lung cancer (NSCLC) that has been demonstrated to induce apoptosis in NSCLC cells by increasing functionally active Fas expression. The aim of this study was to evaluate the Fas/Fas ligand (FasL) system involvement...

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Detalhes bibliográficos
Main Authors: Siena, Liboria, Pace, Elisabetta, Ferraro, Maria, Di Sano, Caterina, Melis, Mario, Profita, Mirella, Spatafora, Mario, Gjomarkaj, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3904245/
https://ncbi.nlm.nih.gov/pubmed/24128051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12190
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