Group II Metabotropic Glutamate Receptor Stimulation Triggers Production and Release of Alzheimer's Amyloid β(42) from Isolated Intact Nerve Terminals

Aberrant accumulation of amyloid β (Aβ) oligomers may underlie the cognitive failure of Alzheimer's disease (AD). All species of Aβ peptides are produced physiologically during normal brain activity. Therefore, elucidation of mechanisms that interconnect excitatory glutamatergic neurotransmissi...

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Bibliografiska uppgifter
Huvudupphovsmän: Kim, Soong Ho, Fraser, Paul E., Westaway, David, St. George-Hyslop, Peter H., Ehrlich, Michelle E., Gandy, Sam
Materialtyp: Artigo
Språk:Inglês
Publicerad: Society for Neuroscience 2010
Ämnen:
Brief Communications
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857209/
https://ncbi.nlm.nih.gov/pubmed/20237257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4717-09.2010
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