Group II Metabotropic Glutamate Receptor Stimulation Triggers Production and Release of Alzheimer's Amyloid β(42) from Isolated Intact Nerve Terminals

Aberrant accumulation of amyloid β (Aβ) oligomers may underlie the cognitive failure of Alzheimer's disease (AD). All species of Aβ peptides are produced physiologically during normal brain activity. Therefore, elucidation of mechanisms that interconnect excitatory glutamatergic neurotransmissi...

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Detalhes bibliográficos
Main Authors: Kim, Soong Ho, Fraser, Paul E., Westaway, David, St. George-Hyslop, Peter H., Ehrlich, Michelle E., Gandy, Sam
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2010
Assuntos:
Brief Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857209/
https://ncbi.nlm.nih.gov/pubmed/20237257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4717-09.2010
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