Group II Metabotropic Glutamate Receptor Stimulation Triggers Production and Release of Alzheimer's Amyloid β(42) from Isolated Intact Nerve Terminals

Aberrant accumulation of amyloid β (Aβ) oligomers may underlie the cognitive failure of Alzheimer's disease (AD). All species of Aβ peptides are produced physiologically during normal brain activity. Therefore, elucidation of mechanisms that interconnect excitatory glutamatergic neurotransmissi...

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Main Authors: Kim, Soong Ho, Fraser, Paul E., Westaway, David, St. George-Hyslop, Peter H., Ehrlich, Michelle E., Gandy, Sam
Formáid: Artigo
Teanga:Inglês
Foilsithe: Society for Neuroscience 2010
Ábhair:
Brief Communications
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857209/
https://ncbi.nlm.nih.gov/pubmed/20237257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4717-09.2010
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