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Single-nucleotide Polymorphisms in the p53 Signaling Pathway
The p53 tumor suppressor pathway is central both in reducing cancer frequency in vertebrates and in mediating the response of commonly used cancer therapies. This article aims to summarize and discuss a large body of evidence suggesting that the p53 pathway harbors functional inherited single-nucleo...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Cold Spring Harbor Laboratory Press
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2857176/ https://ncbi.nlm.nih.gov/pubmed/20452958 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a001032 |
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