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Single-nucleotide Polymorphisms in the p53 Signaling Pathway

The p53 tumor suppressor pathway is central both in reducing cancer frequency in vertebrates and in mediating the response of commonly used cancer therapies. This article aims to summarize and discuss a large body of evidence suggesting that the p53 pathway harbors functional inherited single-nucleo...

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Detalhes bibliográficos
Main Authors: Grochola, Lukasz F., Zeron-Medina, Jorge, Mériaux, Sophie, Bond, Gareth L.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857176/
https://ncbi.nlm.nih.gov/pubmed/20452958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a001032
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