Single-nucleotide Polymorphisms in p53 Pathway and Aggressiveness of Prostate Cancer in a Caucasian Population

PURPOSE: The tumor suppressor p53 plays a crucial role in maintaining genomic stability and tumor prevention. Mdm2, Mdm4 and Hausp are all critical regulators of the p53 protein. Despite the importance of p53 pathway in prostate cancer development and progression, little is known about the associati...

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Detalhes bibliográficos
Principais autores: Sun, Tong, Lee, Gwo-Shu Mary, Oh, William K., Pomerantz, Mark, Yang, Ming, Xie, Wanling, Freedman, Matthew L., Kantoff, Philip W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2970725/
https://ncbi.nlm.nih.gov/pubmed/20855462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-1261
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