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Single-nucleotide polymorphisms in the p53 pathway regulate fertility in humans

The tumor suppressor protein p53 plays an important role in maternal reproduction in mice through transcriptional regulation of leukemia inhibitory factor (LIF), a cytokine crucial for blastocyst implantation. To determine whether these observations could be extended to humans, a list of single-nucl...

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Detalhes bibliográficos
Main Authors: Kang, Hey-Joo, Feng, Zhaohui, Sun, Yvonne, Atwal, Gurinder, Murphy, Maureen E., Rebbeck, Timothy R., Rosenwaks, Zev, Levine, Arnold J., Hu, Wenwei
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2700980/
https://ncbi.nlm.nih.gov/pubmed/19470478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0904280106
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