Single-nucleotide polymorphisms in the p53 pathway regulate fertility in humans

The tumor suppressor protein p53 plays an important role in maternal reproduction in mice through transcriptional regulation of leukemia inhibitory factor (LIF), a cytokine crucial for blastocyst implantation. To determine whether these observations could be extended to humans, a list of single-nucl...

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Autors principals: Kang, Hey-Joo, Feng, Zhaohui, Sun, Yvonne, Atwal, Gurinder, Murphy, Maureen E., Rebbeck, Timothy R., Rosenwaks, Zev, Levine, Arnold J., Hu, Wenwei
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2009
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2700980/
https://ncbi.nlm.nih.gov/pubmed/19470478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0904280106
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