Single-nucleotide polymorphisms in the p53 pathway regulate fertility in humans

The tumor suppressor protein p53 plays an important role in maternal reproduction in mice through transcriptional regulation of leukemia inhibitory factor (LIF), a cytokine crucial for blastocyst implantation. To determine whether these observations could be extended to humans, a list of single-nucl...

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Bibliografiske detaljer
Main Authors: Kang, Hey-Joo, Feng, Zhaohui, Sun, Yvonne, Atwal, Gurinder, Murphy, Maureen E., Rebbeck, Timothy R., Rosenwaks, Zev, Levine, Arnold J., Hu, Wenwei
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2009
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2700980/
https://ncbi.nlm.nih.gov/pubmed/19470478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0904280106
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