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WDR20 Regulates Activity of the USP12·UAF1 Deubiquitinating Enzyme Complex

The UAF1 (Usp1-associated factor 1) protein binds and stimulates three deubiquitinating enzymes: USP1, USP12, and USP46. Although the USP1·UAF1 complex is required for regulation of the Fanconi anemia (FA) DNA repair pathway, less is known about the USP12·UAF1 and the USP46·UAF1 complexes. To unders...

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Autors principals: Kee, Younghoon, Yang, Kailin, Cohn, Martin A., Haas, Wilhelm, Gygi, Steven P., D'Andrea, Alan D.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857003/
https://ncbi.nlm.nih.gov/pubmed/20147737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.095141
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