The WD40-Repeat Protein WDR-20 and the Deubiquitinating Enzyme USP-46 Promote Cell Surface Levels of Glutamate Receptors

Reversible modification of AMPA receptors (AMPARs) with ubiquitin regulates receptor levels at synapses and controls synaptic strength. The conserved deubiquitinating enzyme (DUB) ubiquitin-specific protease-46 (USP-46) removes ubiquitin from AMPARs and protects them from degradation in both Caenorh...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Hodul, Molly, Rennich, Bethany J., Luth, Eric S., Dahlberg, Caroline L., Juo, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2021
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8026351/
https://ncbi.nlm.nih.gov/pubmed/33622778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1074-20.2021
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