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Ric-8B Stabilizes the α Subunit of Stimulatory G Protein by Inhibiting Its Ubiquitination

The α subunit of stimulatory G protein (Gα(s)) activates adenylyl cyclase, which catalyzes cAMP production, and regulates many physiological aspects, such as cardiac regulation and endocrine systems. Ric-8B (resistance to inhibitors of cholinesterase 8B) has been identified as the Gα(s)-binding prot...

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Autors principals: Nagai, Yusuke, Nishimura, Akiyuki, Tago, Kenji, Mizuno, Norikazu, Itoh, Hiroshi
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856988/
https://ncbi.nlm.nih.gov/pubmed/20133939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.063313
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