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Activity-based Proteomics of Enzyme Superfamilies: Serine Hydrolases as a Case Study

Genome sequencing projects have uncovered thousands of uncharacterized enzymes in eukaryotic and prokaryotic organisms. Deciphering the physiological functions of enzymes requires tools to profile and perturb their activities in native biological systems. Activity-based protein profiling has emerged...

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Detalhes bibliográficos
Main Authors: Simon, Gabriel M., Cravatt, Benjamin F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856978/
https://ncbi.nlm.nih.gov/pubmed/20147750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R109.097600
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