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Conformational plasticity of the coiled coil domain of BmrR is required for bmr operator binding - the structure of unliganded BmrR

The multidrug-binding transcription regulator, BmrR, from Bacillus subtilis is a MerR family member that binds to a wide array of cationic lipophilic toxins to activate transcription of the multidrug efflux pump gene, bmr. Transcription activation from the σ(A)-dependent bmr operator requires BmrR t...

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Detalhes bibliográficos
Main Authors: Kumaraswami, Muthiah, Newberry, Kate J., Brennan, Richard G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856848/
https://ncbi.nlm.nih.gov/pubmed/20230832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.03.011
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