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Structural contributions to multidrug recognition in the multidrug resistance (MDR) gene regulator, BmrR

Current views of multidrug (MD) recognition focus on large drug-binding cavities with flexible elements. However, MD recognition in BmrR is supported by a small, rigid drug-binding pocket. Here, a detailed description of MD binding by the noncanonical BmrR protein is offered through the combined use...

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Библиографические подробности
Главные авторы: Bachas, Sharrol, Eginton, Christopher, Gunio, Drew, Wade, Herschel
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2011
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131311/
https://ncbi.nlm.nih.gov/pubmed/21690368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1104850108
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