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Conformational plasticity of the coiled coil domain of BmrR is required for bmr operator binding - the structure of unliganded BmrR
The multidrug-binding transcription regulator, BmrR, from Bacillus subtilis is a MerR family member that binds to a wide array of cationic lipophilic toxins to activate transcription of the multidrug efflux pump gene, bmr. Transcription activation from the σ(A)-dependent bmr operator requires BmrR t...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2856848/ https://ncbi.nlm.nih.gov/pubmed/20230832 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.03.011 |
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