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Structural contributions to multidrug recognition in the multidrug resistance (MDR) gene regulator, BmrR
Current views of multidrug (MD) recognition focus on large drug-binding cavities with flexible elements. However, MD recognition in BmrR is supported by a small, rigid drug-binding pocket. Here, a detailed description of MD binding by the noncanonical BmrR protein is offered through the combined use...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3131311/ https://ncbi.nlm.nih.gov/pubmed/21690368 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1104850108 |
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