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Polyphosphate binds with high affinity to exosite II of thrombin
BACKGROUND: Polyphosphate (a linear polymer of inorganic phosphate) is secreted from platelet dense granules and we recently showed that it accelerates factor V activation by thrombin. OBJECTIVE: To examine the interaction of polyphosphate with thrombin. METHODS AND RESULTS: Thrombin, but not prothr...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2856763/ https://ncbi.nlm.nih.gov/pubmed/20002544 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1538-7836.2009.03723.x |
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