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Polymerase incorporation and miscoding properties of 5-chlorouracil
Inflammation-mediated hypochlorous acid (HOCl) can damage DNA, DNA precursors, and other biological molecules, thereby producing an array of damage products such as 5-chlorouracil (ClU). In this study, we prepared and studied 5-chloro-2’-deoxyuridine (CldU) and ClU-containing oligonucleotide templat...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2856725/ https://ncbi.nlm.nih.gov/pubmed/20104909 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx900302j |
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