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Myostatin Is Upregulated Following Stress in an Erk-Dependent Manner and Negatively Regulates Cardiomyocyte Growth in Culture and in a Mouse Model

Myostatin is well established as a negative regulator of skeletal muscle growth, but its role in the heart is controversial. Our goal in this study was to characterize myostatin regulation following cardiomyocyte stress and to examine the role of myostatin in the regulation of cardiomyocyte size. Ne...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Bish, Lawrence T., Morine, Kevin J., Sleeper, Meg M., Sweeney, H. Lee
التنسيق: Artigo
اللغة:Inglês
منشور في: Public Library of Science 2010
الموضوعات:
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856679/
https://ncbi.nlm.nih.gov/pubmed/20419100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010230
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