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A small region in the Angiotensin-Converting Enzyme distal ectodomain is required for cleavage-secretion of the protein at the plasma membrane
Both germinal and somatic isoforms of ACE are type I ectoproteins expressed on the cell surface from where the enzymatically active ectodomains are released to circulation by a regulated cleavage-secretion process. Our previous studies have shown that ACE-secretase activity is regulated by the ACE d...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2856600/ https://ncbi.nlm.nih.gov/pubmed/18636749 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800702a |
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