Roles of the juxtamembrane and extracellular domains of angiotensin-converting enzyme in ectodomain shedding.

Angiotensin-converting enzyme (ACE) is one of a growing number of integral membrane proteins that is shed from the cell surface through proteolytic cleavage by a secretase. To investigate the requirements for ectodomain shedding, we replaced the glycosylphosphatidylinositol addition sequence in memb...

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Détails bibliographiques
Auteurs principaux: Pang, S, Chubb, A J, Schwager, S L, Ehlers, M R, Sturrock, E D, Hooper, N M
Format: Artigo
Langue:Inglês
Publié: 2001
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222046/
https://ncbi.nlm.nih.gov/pubmed/11485566
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