Ectodomain shedding of angiotensin converting enzyme 2 in human airway epithelia

Angiotensin-converting enzyme 2 (ACE2) is a terminal carboxypeptidase and the receptor for the SARS and NL63 coronaviruses (CoV). Loss of ACE2 function is implicated in severe acute respiratory syndrome (SARS) pathogenesis, but little is known about ACE2 biogenesis and activity in the airways. We re...

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Bibliografiska uppgifter
Huvudupphovsmän: Jia, Hong Peng, Look, Dwight C., Tan, Ping, Shi, Lei, Hickey, Melissa, Gakhar, Lokesh, Chappell, Mark C., Wohlford-Lenane, Christine, McCray, Paul B.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Physiological Society 2009
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711803/
https://ncbi.nlm.nih.gov/pubmed/19411314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00071.2009
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