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Profiling epigenetic inactivation of tumor suppressor genes in tumors and plasma from cutaneous melanoma patients

Aberrant methylation of CpG islands in promoter regions of tumor suppressor genes (TSG) has been demonstrated in epithelial origin tumors. However, the methylation profiling of tumor-related gene promoter regions in cutaneous melanoma tumors has not been reported. Seven known or candidate TSGs that...

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Bibliografiske detaljer
Main Authors: Hoon, Dave SB, Spugnardi, Mia, Kuo, Christine, Huang, Sharon K, Morton, Donald L, Taback, Bret
Format: Artigo
Sprog:Inglês
Udgivet: 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856469/
https://ncbi.nlm.nih.gov/pubmed/15064737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1207505
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