AIM1 and LINE-1 Epigenetic Aberrations In Tumor and Serum Relate to Melanoma Progression and Disease Outcome

Aberrations in the methylation status of non-coding genomic repeat DNA sequences and specific gene promoter region are important epigenetic events in melanoma progression. Promoter methylation status in LINE-1 and Absent in melanoma-1(AIM1;6q21) associated with melanoma progression and disease outco...

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Détails bibliographiques
Auteurs principaux: Hoshimoto, Sojun, Kuo, Christine, Chong, Kelly, Takeshima, Ling, Takei, Yoshiki, Li, Michelle, Huang, Sharon, Sim, Myung-Shin, Morton, Donald L., Hoon, Dave S.B.
Format: Artigo
Langue:Inglês
Publié: 2012
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3352986/
https://ncbi.nlm.nih.gov/pubmed/22402438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2012.36
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