Profiling epigenetic inactivation of tumor suppressor genes in tumors and plasma from cutaneous melanoma patients

Aberrant methylation of CpG islands in promoter regions of tumor suppressor genes (TSG) has been demonstrated in epithelial origin tumors. However, the methylation profiling of tumor-related gene promoter regions in cutaneous melanoma tumors has not been reported. Seven known or candidate TSGs that...

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Bibliographic Details
Main Authors: Hoon, Dave SB, Spugnardi, Mia, Kuo, Christine, Huang, Sharon K, Morton, Donald L, Taback, Bret
Format: Artigo
Language:Inglês
Published: 2004
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856469/
https://ncbi.nlm.nih.gov/pubmed/15064737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1207505
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