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Profiling epigenetic inactivation of tumor suppressor genes in tumors and plasma from cutaneous melanoma patients

Aberrant methylation of CpG islands in promoter regions of tumor suppressor genes (TSG) has been demonstrated in epithelial origin tumors. However, the methylation profiling of tumor-related gene promoter regions in cutaneous melanoma tumors has not been reported. Seven known or candidate TSGs that...

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Detalhes bibliográficos
Main Authors: Hoon, Dave SB, Spugnardi, Mia, Kuo, Christine, Huang, Sharon K, Morton, Donald L, Taback, Bret
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856469/
https://ncbi.nlm.nih.gov/pubmed/15064737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1207505
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