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Chemical Induction of Misfolded Prion Protein Conformers in Cell Culture
Prion-infected cells accumulate a heterogeneous population of aberrantly folded PrP conformers, including the disease-causing isoform (PrP(Sc)). We found that specific chemicals can modulate the levels of various PrP conformers in cultured cells. Positively charged polyamidoamines (dendrimers) elimi...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2856248/ https://ncbi.nlm.nih.gov/pubmed/19955177 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.045112 |
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