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Cultured Cell Sublines Highly Susceptible to Prion Infection

Cultured cell lines infected with prions produce an abnormal isoform of the prion protein (PrP(Sc)). In order to derive cell lines producing sufficient quantities of PrP(Sc) for most studies, it has been necessary to subclone infected cultures and select the subclones producing the largest amounts o...

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Detalhes bibliográficos
Main Authors: Bosque, Patrick J., Prusiner, Stanley B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC111954/
https://ncbi.nlm.nih.gov/pubmed/10756052
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