Branched Polyamines Cure Prion-Infected Neuroblastoma Cells

Branched polyamines, including polyamidoamine and polypropyleneimine (PPI) dendrimers, are able to purge PrP(Sc), the disease-causing isoform of the prion protein, from scrapie-infected neuroblastoma (ScN2a) cells in culture (S. Supattapone, H.-O. B. Nguyen, F. E. Cohen, S. B. Prusiner, and M. R. Sc...

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Main Authors: Supattapone, Surachai, Wille, Holger, Uyechi, Lisa, Safar, Jiri, Tremblay, Patrick, Szoka, Francis C., Cohen, Fred E., Prusiner, Stanley B., Scott, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2001
Assuntos:
Virus-Cell Interactions
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC114138/
https://ncbi.nlm.nih.gov/pubmed/11238871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.7.3453-3461.2001
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