تحميل...
Continuous Quinacrine Treatment Results in the Formation of Drug-Resistant Prions
Quinacrine is a potent antiprion compound in cell culture models of prion disease but has failed to show efficacy in animal bioassays and human clinical trials. Previous studies demonstrated that quinacrine inefficiently penetrates the blood-brain barrier (BBB), which could contribute to its lack of...
محفوظ في:
| المؤلفون الرئيسيون: | , , , , , , |
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| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
Public Library of Science
2009
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2777304/ https://ncbi.nlm.nih.gov/pubmed/19956709 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000673 |
| الوسوم: |
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