טוען...
Polycystin-1 Protein Level Determines Activity of the Gα(12)/JNK Apoptosis Pathway
Mutations in PKD1 are the most common cause of autosomal dominant polycystic kidney disease (ADPKD). The protein product of PKD1 (polycystin-1 (PC1)) is a large transmembrane protein with a short intracellular C terminus that interacts with numerous signaling molecules, including Gα(12). Cyst format...
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| Main Authors: | , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society for Biochemistry and Molecular Biology
2010
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2856229/ https://ncbi.nlm.nih.gov/pubmed/20106977 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.070821 |
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