Population pharmacokinetics of melphalan in patients with multiple myeloma undergoing high dose therapy

AIMS: To i) investigate the pharmacokinetics of total and unbound plasma melphalan using a population approach, ii) identify clinical factors that affect melphalan disposition and iii) evaluate the role of melphalan exposure in melphalan-related toxicity and disease response. METHODS: Population pha...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Nath, Christa E, Shaw, Peter J, Trotman, Judith, Zeng, Lihua, Duffull, Stephen B, Hegarty, Gareth, McLachlan, Andrew J, Gurney, Howard, Kerridge, Ian, Kwan, Yiu Lam, Presgrave, Peter, Tiley, Campbell, Joshua, Douglas, Earl, John
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Blackwell Science Inc 2010
Gaiak:
Pharmacokinetics
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856049/
https://ncbi.nlm.nih.gov/pubmed/20573084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2010.03638.x
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