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Melphalan pharmacokinetics in children with malignant disease: influence of body weight, renal function, carboplatin therapy and total body irradiation

AIM: To analyse the pharmacokinetics of melphalan in 52 children (0.3–18 years) and determine whether any clinical factors affect the pharmacokinetic parameters Additionally, to examine whether a test melphalan dose can predict the pharmacokinetics of a full dose, when there are 5 intervening days o...

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Detalhes bibliográficos
Main Authors: Nath, Christa E, Shaw, Peter J, Montgomery, Kay, Earl, John W
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884786/
https://ncbi.nlm.nih.gov/pubmed/15752378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2004.02319.x
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