The pharmacokinetic advantages of isolated limb perfusion with melphalan for malignant melanoma.

We describe melphalan pharmacokinetics in 26 patients treated by isolated limb perfusion (ILP). Group A (n = 11) were treated with a bolus of melphalan (1.5 mg kg-1), and in a phase I study the dose was increased to 1.75 mg kg-1. The higher dose was given as a bolus to Group B (n = 9), and by divide...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Scott, R. N., Kerr, D. J., Blackie, R., Hughes, J., Burnside, G., MacKie, R. M., Byrne, D. S., McKay, A. J.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1992
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1977921/
https://ncbi.nlm.nih.gov/pubmed/1637666
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker