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Population pharmacokinetics of carboplatin, etoposide and melphalan in children: a re‐evaluation of paediatric dosing formulas for carboplatin in patients with normal or mild impairment of renal function

AIMS: Carboplatin dosage is calculated by using the estimated glomerular filtration rate (GFR) to achieve a target plasma area under the plasma concentration–time curve (AUC). The aims of the present study were to investigate factors that influence the pharmacokinetics of carboplatin in children wit...

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Detalhes bibliográficos
Publicado no:Br J Clin Pharmacol
Main Authors: Duong, J.K., Veal, G.J., Nath, C.E., Shaw, P.J., Errington, J., Ladenstein, R., Boddy, A.V.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6303207/
https://ncbi.nlm.nih.gov/pubmed/30261554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13774
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