Lymph node–resident lymphatic endothelial cells mediate peripheral tolerance via Aire-independent direct antigen presentation

Peripheral immune tolerance is generally thought to result from cross-presentation of tissue-derived proteins by quiescent tissue-resident dendritic cells to self-reactive T cells that have escaped thymic negative selection, leading to anergy or deletion. Recently, we and others have implicated the...

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Bibliografiska uppgifter
Huvudupphovsmän: Cohen, Jarish N., Guidi, Cynthia J., Tewalt, Eric F., Qiao, Hui, Rouhani, Sherin J., Ruddell, Alanna, Farr, Andrew G., Tung, Kenneth S., Engelhard, Victor H.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2010
Ämnen:
Brief Definitive Report
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856027/
https://ncbi.nlm.nih.gov/pubmed/20308365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20092465
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