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TDP-43 in Neurodegenerative Disorders

BACKGROUND: The number of neurodegenerative diseases associated with pathological aggregates of TAR DNA-binding protein 43 (TDP-43) has increased, leading to the new designation “TDP-43 proteinopathy.” Biochemically, TDP-43 proteinopathies are characterized by decreased solubility, hyperphosphorylat...

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Detalhes bibliográficos
Main Authors: Cook, Casey, Zhang, Yong-Jie, Xu, Ya-fei, Dickson, Dennis W., Petrucelli, Leonard
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2855963/
https://ncbi.nlm.nih.gov/pubmed/18549326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14712598.8.7.969
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