Multi-site assessment of the precision and reproducibility of multiple reaction monitoring–based measurements of proteins in plasma

Verification of candidate biomarkers relies upon specific, quantitative assays optimized for selective detection of target proteins, and is increasingly viewed as a critical step in the discovery pipeline that bridges unbiased biomarker discovery to preclinical validation. Although individual labora...

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Hauptverfasser: Addona, Terri A, Abbatiello, Susan E, Schilling, Birgit, Skates, Steven J, Mani, D R, Bunk, David M, Spiegelman, Clifford H, Zimmerman, Lisa J, Ham, Amy-Joan L, Keshishian, Hasmik, Hall, Steven C, Allen, Simon, Blackman, Ronald K, Borchers, Christoph H, Buck, Charles, Cardasis, Helene L, Cusack, Michael P, Dodder, Nathan G, Gibson, Bradford W, Held, Jason M, Hiltke, Tara, Jackson, Angela, Johansen, Eric B, Kinsinger, Christopher R, Li, Jing, Mesri, Mehdi, Neubert, Thomas A, Niles, Richard K, Pulsipher, Trenton C, Ransohoff, David, Rodriguez, Henry, Rudnick, Paul A, Smith, Derek, Tabb, David L, Tegeler, Tony J, Variyath, Asokan M, Vega-Montoto, Lorenzo J, Wahlander, Åsa, Waldemarson, Sofia, Wang, Mu, Whiteaker, Jeffrey R, Zhao, Lei, Anderson, N Leigh, Fisher, Susan J, Liebler, Daniel C, Paulovich, Amanda G, Regnier, Fred E, Tempst, Paul, Carr, Steven A
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2855883/
https://ncbi.nlm.nih.gov/pubmed/19561596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.1546
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