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The optimization of in vitro high-throughput chemical lysis of Escherichia coli. Application to ACP domain of the polyketide synthase ppsC from Mycobacterium tuberculosis

Protein production in Escherichia coli involves high-level expression in a culture, followed by harvesting of the cells and finally their disruption, or lysis, to release the expressed proteins. We compare three high-throughput chemical lysis methods to sonication, using a robotic platform and metho...

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Detalhes bibliográficos
Main Authors: Listwan, Pawel, Pédelacq, Jean-Denis, Lockard, Meghan, Bell, Carolyn, Terwilliger, Thomas C., Waldo, Geoffrey S.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2855807/
https://ncbi.nlm.nih.gov/pubmed/20069378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10969-009-9077-8
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