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Hydroxymalonyl-acyl carrier protein (ACP) and aminomalonyl-ACP are two additional type I polyketide synthase extender units

Combinatorial biosynthesis of type I polyketide synthases is a promising approach for the generation of new structural derivatives of polyketide-containing natural products. A target of this approach has been to change the extender units incorporated into a polyketide backbone to alter the structure...

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Hlavní autoři: Chan, Yolande A., Boyne, Michael T., Podevels, Angela M., Klimowicz, Amy K., Handelsman, Jo, Kelleher, Neil L., Thomas, Michael G.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1599966/
https://ncbi.nlm.nih.gov/pubmed/16983083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0603748103
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