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Upregulation of Nox4 by hypertrophic stimuli promotes apoptosis and mitochondrial dysfunction in cardiac myocytes
RATIONALE: NADPH oxidases are a major source of superoxide (O(2)(−)) in the cardiovascular system. The function of Nox4, a member of the Nox family of NADPH oxidases, in the heart is poorly understood. OBJECTIVE: The goal of this study was to elucidate the role of Nox4 in mediating oxidative stress...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2855780/ https://ncbi.nlm.nih.gov/pubmed/20185797 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.109.213116 |
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