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Synthesis of isotopically labeled P-site substrates for the ribosomal peptidyl transferase reaction
Isotopomers of the ribosomal P-site substrate, the trinucleotide peptide conjugate CCA-pcb,1 have been designed and synthesized in 26–350020steps. These include individual isotopic substitution at the α-proton, carbonyl carbon, and carbonyl oxygen of the amino acid, the O2' and O3' of the...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2007
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2855649/ https://ncbi.nlm.nih.gov/pubmed/18081346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo702070m |
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