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Effect of O(6)-Alkylguanine-DNA Alkyltransferase on Genotoxicity of Epihalohydrins
The effect of O(6)-alkylguanine-DNA alkyltransferase (AGT) on the toxicity and mutagenicity of epihalohydrins was studied. AGT is a DNA repair protein that protects cells from agents that produce genotoxic O(6)-alkylguanine lesions by transferring the alkyl group to an internal cysteine residue (Cys...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2009
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2855547/ https://ncbi.nlm.nih.gov/pubmed/19472322 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.20491 |
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