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Effect of O(6)-Alkylguanine-DNA Alkyltransferase on Genotoxicity of Epihalohydrins

The effect of O(6)-alkylguanine-DNA alkyltransferase (AGT) on the toxicity and mutagenicity of epihalohydrins was studied. AGT is a DNA repair protein that protects cells from agents that produce genotoxic O(6)-alkylguanine lesions by transferring the alkyl group to an internal cysteine residue (Cys...

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書誌詳細
主要な著者: Kalapila, Aley G., Loktionova, Natalia A., Pegg, Anthony E.
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2855547/
https://ncbi.nlm.nih.gov/pubmed/19472322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.20491
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