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Titin-Isoform Dependence of Titin-Actin Interaction and Its Regulation by S100A1/Ca(2+) in Skinned Myocardium

Titin, also known as connectin, is a large filamentous protein that greatly contributes to passive myocardial stiffness. In vitro evidence suggests that one of titin's spring elements, the PEVK, interacts with actin and that this adds a viscous component to passive stiffness. Differential splic...

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書目詳細資料
Main Authors: Fukushima, Hideto, Chung, Charles S., Granzier, Henk
格式: Artigo
語言:Inglês
出版: Hindawi Publishing Corporation 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2855102/
https://ncbi.nlm.nih.gov/pubmed/20414336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/727239
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