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Structural and chemical basis for glucosamine-6-phosphate binding and activation of the glmS ribozyme

The glmS ribozyme is the first naturally occurring catalytic RNA that relies on an exogenous, non-nucleotide cofactor for reactivity. From a biochemical perspective, the glmS ribozyme derived from Bacillus anthracis is the best characterized. However, much of the structural work to date has been don...

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Библиографические подробности
Главные авторы: Cochrane, Jesse C., Lipchock, Sarah V., Smith, Kathryn D., Strobel, Scott A.
Формат: Artigo
Язык:Inglês
Опубликовано: 2009
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2854835/
https://ncbi.nlm.nih.gov/pubmed/19228039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi802069p
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